LSIL.pdf

의료인을 위한 유튜브 링크 : https://youtu.be/dAKO0hIcd7s

자궁경부암은 HPV 바이러스에 의해 생기는 것으로 알려진 여성의 생식기 암이다

자궁 경부암은 증상이 없기 때문에 pap smear, 즉 자궁 경부암 검사를 통해 최근에 조기에 발견되고 있다.

LSIL은 low grade squamous intraepithelial cell의 약자로 의미를 요약하자면 암이 될 확률이 있기는 하지만 비교적 낮은 세포 병변을 보이는 것이다.

LSIL은 위험도가 ASCUS보다는 높지만 침습성 암으로 발전할 가능성이 낮다.

LSIL의 조치는 인유두암바이러스 검사 결과에 따라 달라진다.

검사 결과 인유두암바이러스에 걸렸거나 검사결과가 없으면 자궁경관을 관찰하고 필요시 생검을 진행하지만,

인유두암 바이러스에 안 걸렸을 경우 단순히 관찰할 수 있다.

1. Definition
LSIL is a result of pap smear, standing for low grade squamous intraepithelial lesion.

2. Significance
Pap smear is a screening test for cervical cancer and LSIL is the result meaning comparatively low risk of developing into cervical cancer, though it is more risky than ASCUS.

However, it is important to note that LSILs are highly associated with HPV infection, amounting 77%

3. Management
So how do we manage LSIL?
Here is the diagram.

patient with LSIL may have precancerous lesion, but is not d

 

iagnosed with cancer.
First, the patient may or may not be tested for HPV.
If the patient was not tested or showed positive result, the patient may be examined by colposcopy. If coploscopy shows negative results, mostly CIN, grade 2 or 3 will be treated with excision or ablation.

But in case colposcopy shows low grade lesions or no lesions at all, co-testing at one year or diagnostic excisional procedure will be done.

If patients are tested with HPV and the result is negative, the patient may repeat cotesting in one year.

 

If LSIL persists for more than 2 years, ablative treatment may be an option.

3. Attention
But for patients who is 21-24 years old, there is less chance of developing cancer. In this regard, colposcopy is not recommended.

4. Comments
Once you know ASCUS, it is easier to understand LSIL. To understand ASCUS, please refer to my previous video.
Thank you for listening and I will come back with the other results of pap test! See you